you bet - PMC

Ursula Smole, Christian Radauer, Nina Lengger, Martin Svoboda, Neil Rigby, Merima Bublin, Sonja Gaier, Karin Hoffmann-Sommergruber, Erika Jensen-Jarolim, Diana Mechtcheriakova, Heimo Breiteneder

PLoS One. 2015; 10(1): e0117904. Published online 2015 Jan 30. doi: 10.1371/journal.pone.0117904

PMCID:: PMC4311984

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JQ1, a BET inhibitor, controls TLR4-induced IL-10 production in regulatory B cells by BRD4-NF-κB axis

Min Bum Lee, Jun-Ho Lee, Seong Hwi Hong, Jueng Soo You, Seung Taek Nam, Hyun Woo Kim, Young Hwan Park, Dajeong Lee, Keun Young Min, Yeong-Min Park, Young Mi Kim, Hyuk Soon Kim, Wahn Soo Choi

BMB Rep. 2017 Dec; 50(12): 640–646. Published online 2017 Dec 31. doi: 10.5483/BMBRep.2017.50.12.194

PMCID:: PMC5749911

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Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression

Chong Qin, Yang Hu, Bing Zhou, Ester Fernandez-Salas, Chao-Yie Yang, Liu Liu, Donna McEachern, Sally Przybranowski, Mi Wang, Jeanne Stuckey, Jennifer Meagher, Longchuan Bai, Zhuo Chen, Mei Lin, Jiuling Yang, Fuming Xu, Jiantao Hu, Weiguo Xing, Liyue Huang, Siwei Li, Bo Wen, Duxin Sun, Shaomeng Wang

J Med Chem. Author manuscript; available in PMC 2019 Aug 9.

Published in final edited form as: J Med Chem. 2018 Aug 9; 61(15): 6685–6704. Published online 2018 Jul 18. doi: 10.1021/acs.jmedchem.8b00506

PMCID:: PMC6545111

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A deregulated m⁶A writer complex axis driven by BRD4 confers an epitranscriptomic vulnerability in combined DNA repair–targeted therapy

Xiao Lu, Lichao Peng, Jiancheng Ding, Yuanpei Li, Qing Li, Mengchen Rao, Tong Shu, Xiaoniu He, Chen Liu, Jing Ye, Wen Liu, Han You

Proc Natl Acad Sci U S A. 2023 Oct 10; 120(41): e2304534120. Published online 2023 Oct 2. doi: 10.1073/pnas.2304534120

PMCID:: PMC10576145

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Heat shock protein X purified from Mycobacterium tuberculosis enhances the efficacy of dendritic cells-based immunotherapy for the treatment of allergic asthma

Hye-young Kim, Hyun Kyu Kang, Joon Cho, In Duk Jung, Gun Young Yoon, Min-Goo Lee, Sung Jae Shin, Won Sun Park, Jong-Hwan Park, Seung-Wook Ryu, Yeong-Min Park, Ji Chang You

BMB Rep. 2015 Mar; 48(3): 178–183. doi: 10.5483/BMBRep.2015.48.3.257

PMCID:: PMC4453021

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The BET family in immunity and disease

Nian Wang, Runliu Wu, Daolin Tang, Rui Kang

Signal Transduct Target Ther. 2021; 6: 23. Published online 2021 Jan 19. doi: 10.1038/s41392-020-00384-4

PMCID:: PMC7813845

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IL-7 receptor alpha defines heterogeneity and signature of human effector memory CD8⁺ T cells in high dimensional analysis

Min Sun Shin, Dongjoo Kim, Kristina Yim, Hong-Jai Park, Sungyong You, Xuemei Dong, Fotios Koumpouras, Albert C. Shaw, Rong Fan, Smita Krishnaswamy, Insoo Kang

Cell Immunol. Author manuscript; available in PMC 2021 Sep 1.

Published in final edited form as: Cell Immunol. 2020 Sep; 355: 104155. Published online 2020 Jun 24. doi: 10.1016/j.cellimm.2020.104155

PMCID:: PMC7415611

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Yang-Yang Tang, Da-Cheng Wang, You-Yue Chen, Wang-Dong Xu, An-Fang Huang

Front Immunol. 2023; 14: 1305590. Published online 2023 Dec 18. doi: 10.3389/fimmu.2023.1305590

PMCID:: PMC10757975

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BET Proteins: Investigating BRDT as a Potential Target for Male Contraception

Andrea Wisniewski, Gunda I. Georg

Bioorg Med Chem Lett. Author manuscript; available in PMC 2021 Mar 15.

Published in final edited form as: Bioorg Med Chem Lett. 2020 Mar 15; 30(6): 126958. Published online 2020 Jan 21. doi: 10.1016/j.bmcl.2020.126958

PMCID:: PMC7023680

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Balloon Eustachian Tuboplasty: Systematic Review of Long-term Outcomes and Proposed Indications

Veera Luukkainen, Ilkka Kivekäs, Juha Silvola, Jussi Jero, Saku T. Sinkkonen

J Int Adv Otol. 2018 Apr; 14(1): 112–126. Published online 2018 Apr 1. doi: 10.5152/iao.2018.4769

PMCID:: PMC6354503

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Genome-Wide Identification and Characterization of the BRD Family in Nile Tilapia (Oreochromis niloticus)

Chunmei Xu, Miao Yu, Qingqing Zhang, Zhisheng Ma, Kang Du, Huiqin You, Jing Wei, Deshou Wang, Wenjing Tao

Animals (Basel) 2022 Sep; 12(17): 2266. Published online 2022 Sep 1. doi: 10.3390/ani12172266

PMCID:: PMC9454494

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Better than counting seconds: Identifying fallers among healthy elderly using fusion of accelerometer features and dual-task Timed Up and Go

Moacir Ponti, Patricia Bet, Caroline L. Oliveira, Paula C. Castro

PLoS One. 2017; 12(4): e0175559. Published online 2017 Apr 27. doi: 10.1371/journal.pone.0175559

PMCID:: PMC5407756

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Tailoring digital apps to support active ageing in a low income community

Paula Costa Castro, Lua Bonadio Romano, David Frohlich, Lorena Jorge Lorenzi, Lucas Bueno Campos, Andresa Paixão, Patrícia Bet, Marije Deutekom, Ben Krose, Victor Zuniga Dourado, Grace Angélica de Oliveira Gomes

PLoS One. 2020; 15(12): e0242192. Published online 2020 Dec 10. doi: 10.1371/journal.pone.0242192

PMCID:: PMC7728168

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BETP degradation simultaneously targets acute myelogenous leukemic stem cells and the microenvironment

Sujan Piya, Hong Mu, Seemana Bhattacharya, Philip L. Lorenzi, R. Eric Davis, Teresa McQueen, Vivian Ruvolo, Natalia Baran, Zhiqiang Wang, Yimin Qian, Craig M. Crews, Marina Konopleva, Jo Ishizawa, M. James You, Hagop Kantarjian, Michael Andreeff, Gautam Borthakur

J Clin Invest. 2019 May 1; 129(5): 1878–1894. Published online 2019 Apr 2. doi: 10.1172/JCI120654

PMCID:: PMC6486356

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MicroRNA-29b Inhibits Diabetic Nephropathy in db/db Mice

Hai-Yong Chen, Xiang Zhong, Xiao R Huang, Xiao-Ming Meng, Yongke You, Arthur CK Chung, Hui Y Lan

Mol Ther. 2014 Apr; 22(4): 842–853. Prepublished online 2013 Dec 6. Published online 2014 Jan 21. doi: 10.1038/mt.2013.235

PMCID:: PMC3982502

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A New, Better BET: Rescuing and Revising Basic Emotion Theory

Daniel D. Hutto, Ian Robertson, Michael D. Kirchhoff

Front Psychol. 2018; 9: 1217. Published online 2018 Jul 17. doi: 10.3389/fpsyg.2018.01217

PMCID:: PMC6057353

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Figure 1

Questionnaire item used to measure individual-level loss aversion. Imagine that a person wants to make a bet with you. He flips a coin, and if it turns up heads, you lose a certain amount of money, if it turns up tails, you win a certain amount. Which of the following offers do you accept?

Decision-Making in Suicidal Behavior: The Protective Role of Loss Aversion

Front Psychiatry. 2018;9:116.
Figure 4Grand-average difference waveforms and scalp topographies for the difference signals for clear loss – clears win, clear loss – ambivalent win, clear loss – ambivalent loss, and bet 50 € - bet 0 €.

You Do the Math: Coding of Bets and Outcomes in a Gambling Task in the Feedback-Related Negativity and P300 in Healthy Adults

PLoS One. 2013;8(11):e81262.
Figure 2Grand-average ERP waveforms time-locked to feedback onset according to initial bet (0 € or 50 €) and outcome (clear win, ambivalent or clear loss) at electrode FCz (left panel) and Pz (right panel).

You Do the Math: Coding of Bets and Outcomes in a Gambling Task in the Feedback-Related Negativity and P300 in Healthy Adults

PLoS One. 2013;8(11):e81262.
Fig 1Screenshots of the display.

Need game embedded in a lottery frame either as gain (left) or as loss (right). The probability of winning/losing the bet is presented in a pie chart. In a gain trial, the probability of winning is marked in green and the probability of losing in gray. In a loss trial, the probability of winning is marked in gray and the probability of losing in red. Below the pie charts are the number of points displayed from which the donor can bet on: 1, 10, or 50 points. L, C, and R in front of the bets refer to the keys the participant needs to press to indicate her/his choice. The third row in the display shows the current endowment and need of the donor (“you”) and that of the recipient (“Other person”). The last row indicates the remaining time allotted to a given trial.

Gamble for the needy! Does identifiability enhances donation?

PLoS One. 2020;15(6):e0234336.